Decision Trees: Classification and Regression Tree (CART) AlgorithmClassification and Regression Trees (CART) are a popular machine learning technique used for both classification and regression tasks…Jul 10, 2023Jul 10, 2023
Introduction to Missing DataThere are three main mechanisms for missing data: missing completely at random (MCAR), missing at random (MAR), and missing not at random…Jan 29, 2023Jan 29, 2023
Comparisons of Superiority, Non-superiority, Non-inferiority, and Equivalence TrialsThe purpose of a randomized clinical trial (RCT) is to identify a treatment that is superior to standard therapy or placebo. It means an…Dec 6, 2022Dec 6, 2022
Bayesian Optimal Interval Designs (BOIN) for Phase I Clinical TrialsThe BOIN design proposed by Yuan is a statistical methodology for phase I dose-finding clinical trials. In 2021, the FDA granted the BOIN…Dec 4, 2022Dec 4, 2022
Linear Discriminant Analysis with Different ViewsIn general, there are two approaches to the classification problem:Oct 9, 2022Oct 9, 2022
Bayesian Logistic Regression Model (BLRM) for Phase I Clinical TrialThe primary purpose of the phase I clinical trial is to identify the MTD based on the toxicity profile. Please refer to the article for a…Oct 1, 2022Oct 1, 2022
Rule-based Design for Phase I Clinical TrialsThe primary objective of phase I clinical trials is to identify the maximum tolerated dose (MTD) of a new treatment based on the toxicity…Sep 25, 2022Sep 25, 2022
